Clinical Toxicology

ANALYTICAL SERVICES

  • Toxic substance identification in vomit, aspirate, blood, urine etc.
  • Drugs of abuse identification in biological specimens (Blood/Urine).
  • Blood/Urine alcohol estimation.
  • Therapeutic drugs monitoring.
  • Screening of toxic substance in suspected food stuff.
  • Miscellaneous toxic substance/drug analysis.


SUBIMISSION REQUIREMENTS

S. No Sample Quantity Preservation Container
1 Unclothed Blood 10ml. Heparin/amide/fluoride/oxalate/ citrate/EDTA etc. Heparin zed tube or fluoride/oxalate tube.
2 Urine 50ml. - Screw cap container /tube Disposal leak-proof
3 Vomit 50ml/all available - Screw cap container /tube Disposal leak-proof
4 Stomach wash aspirate 50ml.(first wash) - Screw cap container /tube Disposal leak-proof
5 Scene Residue Available - Pack Seperate

Note: For 1ml. blood, 10mg.above mentioned preservative is necessary.

 

BLOOD

It is normally reserved for quantitative assays. Plasma or serum samples are useful in clinical analysis. Because these samples contain fewer interfering substances than whole blood .For carbon monoxide, cyanide and lead poisoning whole blood is needed because these are primarily found in erythrocytes. The space above the blood in the tube (headspace) should be minimized if carbon monoxide poisoning is suspected.

 

URINE

It is useful for screening tests as it is often available in large volumes and usually contains higher concentration of drugs or other poisons than blood. The sample should be obtained as soon as possible, ideally before any drug therapy is initiated.

 

STOMACH CONTENT

(Vomit, gastric aspirate and stomach washing)
It is the best sample on which to perform certain tests. It is important to obtain the first sample of washings, since later samples may be very dilute.

 

SCENE RESIDUE

  • It is important that all bottles or other suspect materials found with of near the patient (scene residues) are retained for analysis since they may be related to poisoning episode.
  • For examination of alcohol/drugs of abuse in blood/urine, the specimens should be collected within 24 hours after consumption.
  • Specimens sent for analysis must be clearly labeled with patient's full name, the date, time of collection and the nature of the specimen.
  • Specimens must be submitted with a request for (Annex-I).
  • Charge: Cases are changed on the basis of tests applied (Ranging from Rs. 300.00 to 1200.00 per case) (Annex-II)

 

INFORMATION

The laboratory does not operate 24 hrs .However specimens pertaining to life-threatening cases will be given top priority. For better influence in clinical management of poisoning the laboratory provides the analysis report within 2-4 hours of receipt of the specimen. An further information can be collected from the laboratory at anytime.

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